Fig. 4
From: Overexpression of CENPF correlates with poor prognosis and tumor bone metastasis in breast cancer
CENPF mRNA expression is higher in bone metastasis than primary BC lesions and other target organs (a). CENPF mRNA expression in primary lesions and brain metastasis does not differ (b). Histopathological diagnosis (H & E staining) of samples from primary lesions (×200), lung metastasis (×200), and bone metastasis (×200) of BALB/C mice 4T1 BC models (c). CENPF and PTHrP in primary lesions (×400), lung metastasis (×400) and bone metastasis (×400) of BALB/C mice 4T1 BC models (d). IHC staining intensity of CENPF and PTHrP is shown (e). Error bars represents the mean ± SD of three replicate samples. *p < 0.05, **p < 0.01