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Fig. 7 | Cancer Cell International

Fig. 7

From: miR-149 inhibits cell proliferation and enhances chemosensitivity by targeting CDC42 and BCL2 in neuroblastoma

Fig. 7

miR-149 regulated NB progression by targeting BCL2. a The expression of BCL2 protein was measured in SK-N-BE(2)C and SK-N-SH cells transfected with miR-NC, miR-149, miR-149 + pcDNA or miR-149 + BCL2 by western blot. The IC50 of Dox (b), cell proliferation (c), colony formation (d) and apoptosis (e) were analyzed in SK-N-BE(2)C and SK-N-SH cells transfected with miR-NC, miR-149, miR-149 + pcDNA or miR-149 + BCL2 by MTT or flow cytometry, respectively. *P < 0.05, **P < 0.01, compared with miR-NC or miR-149 + pcDNA group

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Cancer Cell International

ISSN: 1475-2867

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