Fig. 2

Global overview of the transcriptomics of ccRCC patients. a The t-Distributed Stochastic Neighbor Embedding (t-SNE) plot of global mRNA expression for Chinese (C, n = 55) and TCGA’s (T, n = 533) ccRCC patients. Samples are colored by race. b Heatmap for gene set variation analysis (GSVA) on early (T1T2) and late (T3T4) clinical stages. Cutoffs used for GSVA were:|Fold Change| > 1.3 and Bonferroni & Hochberg adjusted p-value < 0.05