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Fig. 8 | Cancer Cell International

Fig. 8

From: Silenced lncRNA SNHG14 restrains the biological behaviors of bladder cancer cells via regulating microRNA-211-3p/ESM1 axis

Fig. 8

Silenced SNHG14 or elevated miR-211-3p reduces the tumor volume and weight of nude mice with BCa. a The xenografted tumor in nude mice transfected with T24 cells; b The tumor volume in nude mice after transfection with T24 cells; c The tumor weight of nude mice transfected with T24 cells; d TUNEL staining and Ki67 staining of tumor tissue sections in nude mice after transfection with T24 cells; e Cell apoptosis in nude mice after transfection with T24 cells detected by TUNEL staining; f Positive rate of Ki67 in nude mice after transfection with T24 cells detected by immunohistochemical staining; g The xenografted tumor in nude mice transfected with UMUC-3 cells; H. The tumor volume in nude mice after transfection with UMUC-3 cells; i The tumor weight of nude mice transfected with UMUC-3 cells; j TUNEL staining and Ki67 staining of tumor tissue sections in nude mice after transfection with UMUC-3 cells; k Cell apoptosis in nude mice after transfection with UMUC-3 cells detected by TUNEL staining; l Positive rate of Ki67 in nude mice after transfection with UMUC-3 cells detected by immunohistochemical staining; * vs the si-NC group, P < 0.05; ^ vs the mimic NC group, P < 0.05; and vs the si-SNHG14 + inhibitor NC group, P < 0.05; a vs the oe-NC group, P < 0.05; b vs the inhibitor NC group, P < 0.05; c vs the oe-SNHG14 + mimic NC group, P < 0.05. The experiment was repeated independently for 3 times, and the measurement data were expressed as mean ± standard deviation. One-way ANOVA was functioned for comparison among multiple groups, and Tukey’s post hoc test was used for pairwise comparison

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