Effects of in IL-1B/IL-1RN variants on the susceptibility to head and neck cancer in a chinese Han population

Table 6 Relationship of clinical stage with IL-1B/IL-1RN variants in head and neck cancer patients

Gene	SNP ID	Model	Genotype	Head and neck cancer
Gene	SNP ID	Model	Genotype	III-IV	I-II	OR (95% CI)	p
IL-1RN	rs452204	Allele	A	48	190	1
			G	18	90	0.79 (0.44–1.44)	0.442
		Genotype	AA	21	61	1
			AG	6	68	0.28 (0.10–0.78)	0.015*
			GG	6	11	1.71 (0.53–5.47)	0.369
		Dominant	AA	21	61	1
			AG-GG	12	79	0.49 (0.22–1.13)	0.094
		Recessive	AA-AG	27	129	1
			GG	6	11	2.70 (0.87–8.37)	0.085
		Log-additive				0.87 (0.47–1.61)	0.662

SNP single nucleotide polymorphism, OR odds ratio, 95% CI 95% confidence interval
p values were calculated by logistic regression analysis with adjustments for age and gender
*p < 0.05 respects the data is statistically significant

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