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Fig. 3 | Cancer Cell International

Fig. 3

From: Morphological and molecular characteristics of spheroid formation in HT-29 and Caco-2 colorectal cancer cell lines

Fig. 3

Scanning electron microscope (SEM) imaging of HT-29 and Caco-2 derived spheroids. SEM imaging was performed to assess spheroid morphological parameters in more details. Representative SEM images of spheroids shows roundness structure and smooth surfaces of both a Caco-2 and b HT-29 derived spheroids so that it is not possible to distinguish of individual cells. The hollow structures (arrows) in Caco-2 spheroids is its obvious difference compared to HT-29 spheroids with conglomerated appearance. c Representative phase contrast images of hollow core in Caco-2 derived spheroids. Arrows indicate hollow core of Caco-2 spheroids

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Cancer Cell International

ISSN: 1475-2867

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