Fig. 5
From: Antitumor responses in gastric cancer by targeting B7H3 via chimeric antigen receptor T cells
CAR.B7H3-T cells kill cancer stem cells. A–C Surface expressions of A B7H3, B CD133, and C CD276 were detected in tumor cells (adherent) and CSCs (sphere), respectively (****P < 0.0001). D, E Tumor cells (adherent) and CSCs (sphere) were co-culture with CAR.B7H3-T cells, and direct killing was performed using the LDH release assay. F, G ELISA of effector cytokines from CAR-T cells incubated with adherent or sphere tumor cells