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Fig. 3 | Cancer Cell International

Fig. 3

From: Disclosing a metabolic signature of cisplatin resistance in MDA-MB-231 triple-negative breast cancer cells by NMR metabolomics

Fig. 3

Multivariate analysis of spectra of aqueous extracts from MDA-MB-231 cells (S) vs. MDA-MB-231/R cells (R). Score scatter plots of PCA and PLS-DA models (top) and LV1 loadings (bottom), considering the trajectory of the three experimental time-points: t = 0 h (orange triangles, n = 9/cell type), t = 24 h (black squares, n = 9/cell type), t = 48 h (green circles, n = 9/cell type). Validation parameters (R2 and Q.2) are shown for the PLS-DA model. Loadings’ peak assignments are indicated for the metabolites most relevant for group separation according to the color representation of variable importance to projection color (VIP). Abbreviations as defined in Fig. 2

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Cancer Cell International

ISSN: 1475-2867

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