Fig. 3
From: DPY30 promotes colorectal carcinoma metastasis by upregulating ZEB1 transcriptional expression
Knockdown of DPY30 decreases the migratory and invasive capacities of CRC cells in vitro. HT29-shDPY30 and SW480-shDPY30 cells or their control cells were subjected to wound healing assay (A), Transwell migration (B, top), and Matrigel invasion assays (B, bottom) for 24 h and 48 h, respectively. A Effects of DPY30 knockdown on the migratory capabilities of CRC cells. The uncovered areas in the wound healing assays were quantified as a percentage of the original wound area. Statistical analysis of A, right. B Effects of DPY30 knockdown on the migratory and invasive abilities of CRC cells. Quantification of migrated cells through the membrane and invaded cells through Matrigel are presented as proportions relative to their controls. Statistical analysis of B, right. Data are presented as mean ± SEM of three independent experiments. *P < 0.05, **P < 0.01, ***P < 0.001