Fig. 1
From: Cancer stem cells and their niche in cancer progression and therapy
General overview of the components of the CSC niche. Cellular components such as CAFs, TAMs and MSCs and reactions such as inflammation, hypoxia, angiogenesis, and the ECM of the CSC niche promote and support the properties of CSCs. CSC: cancer stem cell, CAF: cancer-associated fibroblast, ECM: extracellular matrix, MSC: mesenchymal stem cells, TAM: tumour-associated macrophages