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Fig. 6 | Cancer Cell International

Fig. 6

From: Tumour cells can escape antiproliferative pressure by interferon-β through immunoediting of interferon receptor expression

Fig. 6

Induction of ISG mRNA upon stimulation with 130 IU/ml IFN-β. a–c: Left panels: kinetics displayed as expression levels normalised to peak values. Gross outliers were excluded (IFIT1: HLE, PH5CH, PLC; IRF1: PH5CH; n = 2). Right panels: absolute expression levels determined at peak time points. d Relative expression levels at selected time points. e Type I IFN receptor mRNA expression in untreated cells. All graphs display mean ± SD of three independent repetitions (exceptions noted above). Absolute expression levels were determined independently of housekeeping genes as 230−Ct/4.2 ng of total RNA. Statistical analysis was performed with one-way ANOVA followed by Tukey’s multiple comparison test

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