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Table 1 Characteristics of studied cell lines

From: Tumour cells can escape antiproliferative pressure by interferon-β through immunoediting of interferon receptor expression

Cell line

Sex

Age

Primary tissue

Viral status

Cluster

Original publication (additional studies):

Year

PH5CH

M

58

Non-neoplastic hepatocytes

anti-HCV antibody

Noguchi and Hirohashi [45]

1996

PLC

M

24

Hepatoma

HBV DNA integrates

HBsAg secretion

Epithelial-like

Alexander et al. [61] ([62,63,64])

1976

HuH1

M

53

Hepatoma

HBV DNA integrates

HBsAg secretion

Epithelial-like

Huh et al.[62] ([63, 64])

1981

HuH6

M

1

Hepatoblastoma

None

Epithelial-like

Doi et al. [65] ([63, 64])

1976

HuH7

M

57

Well-differentiated HCC

None

Epithelial-like

Nakabayashi et al.[66] ([63, 64, 67, 68])

1982

HepG2

M

15

Hepatoblastoma

None

Epithelial-like

Aden et al.[69] ([63, 64, 67, 68])

1979

Hep3B

M

8

Differentiated HCC

HBV DNA integrates

No HBsAg secretion

Epithelial-like

Aden et al.[69] ([63, 64, 67, 68])

1979

HLE

M

68

Undifferentiated HCC

None

Fibroblast-like

Doi et al.[70] ([63, 64, 68])

1975

HLF

M

68

Undifferentiated HCC

None

Fibroblast-like

Doi et al.[70] ([63, 64, 68])

1975

SNU182

M

24

HCC, grade III/IV

HBV DNA integrates

No HBsAg secretion

Fibroblast-like

Park et al. [71] ([62,63,64])

1995

SNU387

F

41

HCC, grade III-IV/IV

HBV DNA integrates

No HBsAg secretion

Fibroblast-like

Park et al. [71] ([62,63,64])

1995

  1. Cluster definition based on Fukuyama et al. [63]