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Table 2 Summary of the cell lines’ functional malignant characteristics

From: Tumour cells can escape antiproliferative pressure by interferon-β through immunoediting of interferon receptor expression

Cell line

Migration rate [Δ wound confl. [%] / h]

Invasiveness

Proliferation [duplications per hour]

Relative growth in 8000 IU/ml IFN-β [%]

PH5CH

1.92 ± 0.58

6%

0.0324 ± 0.0016

53.28 ± 5.15

PLC

0.17 ± 0.04

a

0.0222 ± 0.0022

4.57 ± 9.13

HuH1

0.56 ± 0.10

a

0.0211 ± 0.0023

46.61 ± 9.54

HuH6

1.03 ± 0.59

a

0.0212 ± 0.0033

24.33 ± 21.77

HuH7

1.04 ± 0.44

 > 20%

0.0245 ± 0.0048

23.93 ± 12.49

HepG2

0.59 ± 0.26

a

0.0183 ± 0.0044

55.31 ± 12.18

Hep3B

0.88 ± 0.44

a

0.0181 0.0017

69.67 ± 8.43

HLE

2.21 ± 0.54

 > 35%

0.0328 ± 0.0026

89.38 ± 8.36

HLF

2.19 ± 0.83

 > 35%

0.0283 ± 0.0046

86.24 ± 13.49

SNU182

0.75 ± 0.33

 > 20%

0.0121 ± 0.0008

41.87 ± 21.08

SNU387

1.77 ± 0.81

 > 20%

0.0210 ± 0.0007

42.62 ± 2.05

  1. acount in uncoated control below cut-off (1000/membrane)