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Table 2 Various nano-based platforms plus EGCG in different cancers

From: Epigallocatechin-3-gallate and its nanoformulation in cervical cancer therapy: the role of genes, MicroRNA and DNA methylation patterns

Type of cancer

Type of nano-formulation

Size

Admintsation route

Result (s)

Ref

Breast cancer

Gelatin NPs

200

-

Inhibit HGF in MDA-MD-231 breast cancer cell line

[95]

Prostate cancer

Chitosan NPs

150–200

-

Inhibit the tumor cell growth and proliferation

[88]

Colon cancer

PLGA NPs

127

-

Increase in DNA damage levels of oxaliplatin

[97]

Prostate cancer

PLA-PEG NPs

260

Intra-tumoral

Induction of apoptosis in prostate cancer PC3 cell line; inhibition of angiogenesis

Significant decrease in tumor size in prostate cancer xenograft model

[89]

Bladder cancer

Gold NPs

20–1200

Oral Intra-tumoral or intra-peritoneal

Reduction in tumor volume

[98]

Neuroblastoma

Gold NPs

25.55

-

Induction of apoptosis

[93]

Basal cell carcinoma

Liposomes

157.4, 268.9

Topic and intra-tumoral

Great amount of EGCG deposition in tumor tissues in BCC model in female nude mice

[99]

Brast cancer

Chitosan-coated liposomes

16.4

-

Inhibit the tuomor cell proliferation and induce apoptosis in tumor cells

[87]

Prostate cancer

Ca/Al-NO3 LDH

-

-

Improve anti-tumor activites

[100]

Prostate cancer

Maltodextrin-gum arabic

120

 

Improve anti-tumor activites

[101]

Liver cancer

Ruthenium

73.59

-

Improve anti-tumor activites

[102]