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Fig. 5 | Cancer Cell International

Fig. 5

From: Glucose transporter 3 (GLUT3) promotes lactylation modifications by regulating lactate dehydrogenase A (LDHA) in gastric cancer

Fig. 5

LDHA is highly expressed in gastric cancer and regulates lactylation levels. A, B LDHA, L-lactyl, H3K9, H3K18, and H3K56 levels in normal gastric and gastric cancer tissues determined using immunohistochemistry. C LDHA levels in blood samples from patients at different stages of gastric cancer determined using enzyme-linked immunosorbent assays. D Determination of lentiviral LDHA knockdown efficiency in HGC-27 cells. E, F Knockdown and overexpression of LDHA in AGS and HGC-27 cells, respectively, and western blot of LDHA, L-lactyl, H3K9, H3K18, and H3K56. G LDHA and L-lactyl levels after LDHA knockdown and overexpression determined using immunofluorescence assays

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Cancer Cell International

ISSN: 1475-2867

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