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Fig. 6 | Cancer Cell International

Fig. 6

From: Glucose transporter 3 (GLUT3) promotes lactylation modifications by regulating lactate dehydrogenase A (LDHA) in gastric cancer

Fig. 6

Reversion experiments confirm that GLUT3 promotes gastric cancer cell EMT by regulating LDHA expression. A, B Western blot of GLUT3, LDHA, L-lactyl, H3K9, H3K18, H3K56, N-cad, E-cad, and vimentin in the GLUT3-NC, GLUT3-KD, and GLUT3 knockdown + LDHA overexpression (GLUT3-KD + LDHA-OE) groups. (C) Metastatic capacity of AGS and HGC-27 cells in the GLUT3-NC, GLUT3-KD, and GLUT3-KD + LDHA-OE groups determined using scratch assays. (D) Metastasis and invasiveness of AGS and HGC-27 cells in the GLUT3-NC, GLUT3-KD, and GLUT3-KD + LDHA-OE groups determined using Transwell assays

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Cancer Cell International

ISSN: 1475-2867

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