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Fig. 1 | Cancer Cell International

Fig. 1

From: A pan-cancer analysis indicates long noncoding RNA HAND2-AS1 as a potential prognostic, immunomodulatory and therapeutic biomarker in various cancers including colorectal adenocarcinoma

Fig. 1

Two distinct collections of microarray and next-generation sequencing datasets were acquired and subjected to analysis in order to uncover differentially expressed genes (DEGs) and lncRNAs (DE-lncRNAs) across a range of cancers. Subsequently, a subset of robust interacting DEGs and DE-lncRNAs associated with TNM staging (blue module) were identified, forming the basis for subsequent regulatory network construction and functional enrichment analyses. Finally, a comprehensive series of downstream analyses was carried out, focusing on HAND2-AS1 as the most prominently interacting DE-lncRNA within the regulatory network

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