Fig. 6

JK184 and Prodigiosin inhibit the Hedgehog and Wnt/β-catenin signaling pathways in CD56-OE cells. A Cells were pretreated with 10 nM JK184 for 48 h. Representative images showing protein expression levels of Hedgehog signaling pathway by western blot. B Cells were pretreated with 500 nM Prodigiosin for 48 h. Representative images showing protein expression levels of Wnt/β-catenin signaling pathway by western blot. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001 by one-way ANOVA (A, B)