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Fig. 3 | Cancer Cell International

Fig. 3

From: Single-cell histone chaperones patterns guide intercellular communication of tumor microenvironment that contribute to breast cancer metastases

Fig. 3

NMF clusters of HCs for macrophages and B cells. (A) t-SNE plot of myeloid cells. (B) Bar plot for 10 HCs-mediated macrophages clusters between brain metastasis and liver metastasis patients. (C) Cell–Cell communications between main HCs-mediated macrophage cells to malignant cells by Cellchat analysis. (D) Violin plots of M1 and M2 macrophage-related signatures scores among HCs-mediated macrophages clusters. (E) Heatmap showing significantly different metabolic signaling pathways among HCs-mediated macrophages clusters. (F) Bar plot for 5 HCs-mediated B cells clusters between brain metastasis and liver metastasis patients. (G) Cell–Cell communications between main HCs-mediated B cells to T cells by Cellchat analysis. (H) Heatmap showing the significantly different TFs among HCs-mediated macrophages and B cell clusters

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