Skip to main content
Fig. 5 | Cancer Cell International

Fig. 5

From: Single-cell histone chaperones patterns guide intercellular communication of tumor microenvironment that contribute to breast cancer metastases

Fig. 5

Overall of the prognosis, immunotherapy response and immunity pathways correlations of HCs-mediated cells types in the public bulk RNA-seq cohorts. (A) Box plot of HCs activity between primary and paired brain metastatic tissues in GSE173661 cohort (* p < 0.05). (B) Violin plot of HCs activity between normal and tumor tissues in the TCGA-BRCA cohort (**** p < 0.0001). (C) Bubble plot of OS analyses (data from 5 BC cohorts). (D) Bubble plot of immunotherapy response analyses (data from 8 immunotherapy cohorts with response rate) (E) Heatmap showing significant correlations between cancer immunity cycles and immunoregulation-related pathways with all HCs-mediated cluster scores (* p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001)

Back to article page

Cancer Cell International

ISSN: 1475-2867

Contact us