Fig. 3

The effects of Robinin and CU-T12-9 on HPNE, Mia-PACA2 and PANC-1 viability and proliferation. (A) HPNE, Mia-PACA2 and PANC-1 were exposed to different concentrations of Robinin (500 nM, 1 µM, 5 µM or 10 µM) and CU-T12-9 (1 µM or 5 µM) for 24 h. (B) Proliferation curve of Mia-PACA2 and PANC-1 exposed to control medium in presence with Robinin (1 µM/ml or 5 µM/ml) and Robinin co-cultivated with CU-T12-9 for 24, 48 and 72 h. Data are presented as the means ± standard deviation of 3 independent repeats. *P < 0.05, **P < 0.01, vs. the control group, #P < 0.05, ##P < 0.01, vs. the Robinin co-cultivated with CU-T12-9 group by one-way ANOVA followed by LSD test