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Fig. 3 | Cancer Cell International

Fig. 3

From: Circular RNA circEYA3 promotes the radiation resistance of hepatocellular carcinoma via the IGF2BP2/DTX3L axis

Fig. 3

circEYA3 protects HCC cells from DNA damage, proliferation inhibition, and apoptosis induced by external irradiation. A, B Comet assays were performed to observe DNA damage caused by external irradiation with or without overexpression of circEYA3. C Immunofluorescence experiments were conducted to observe γH2A.X foci in PLC/PRF/5 cells with or without external radiation. D, E Cell proliferation was evaluated using the Cell Counting Kit-8 (CCK-8) assay, revealing that overexpression of circEYA3 suppressed the radiosensitivity of PLC/PRF/5 and HepG2 cells. F, G Flow cytometry was used to detect apoptotic cells after overexpression of circEYA3 with or without X-ray irradiation at 6 Gy

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Cancer Cell International

ISSN: 1475-2867

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