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Fig. 2 | Cancer Cell International

Fig. 2

From: LncRNA AGAP2 antisense RNA 1 stabilized by insulin-like growth factor 2 mRNA binding protein 3 promotes macrophage M2 polarization in clear cell renal cell carcinoma through regulation of the microRNA-9-5p/THBS2/PI3K-Akt pathway

Fig. 2

AGAP2-AS1 induces RCC cell proliferation, invasion and migration, and macrophage polarization. A, B Transfection efficiency of sh-AGAP2-AS1 by RT-qPCR. C, D Cell viability test by CCK-8. E, F Cell proliferation results by EdU assay. G, H Cell invasion results by Transwell assay. I, J  Cell migration results by wound healing assay. K, L The expression levels of M1 and M2 polarization markers in macrophages. * p < 0.05 vs. sh-NC group or sh-NC + M group. # p < 0.05 vs. Vector group or Vector + M group. In the groups, M refers to PMA + THP-1

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Cancer Cell International

ISSN: 1475-2867

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