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Fig. 5 | Cancer Cell International

Fig. 5

From: LncRNA AGAP2 antisense RNA 1 stabilized by insulin-like growth factor 2 mRNA binding protein 3 promotes macrophage M2 polarization in clear cell renal cell carcinoma through regulation of the microRNA-9-5p/THBS2/PI3K-Akt pathway

Fig. 5

AGAP2-AS1/miR-9-5p/THBS2 axis facilitates the malignant characteristics of ccRCC cells and M2 polarization of macrophages. A, B AGAP2-AS1, miR-9-5p and THBS2 expression in each group of cells following sh-AGAP2-AS1 and oe-THBS2 treatment. C, D Cell proliferation ability by EdU assay. E, F Cell invasion ability. G, H Cell migration ability. I, J Expression of PI3K/AKT signaling pathway proteins. K, L Expression of macrophage M1 and M2 polarization markers. * p < 0.05 vs. sh-NC + oe-NC group. # p < 0.05 vs. sh-AGAP2-AS1 + oe-NC group

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Cancer Cell International

ISSN: 1475-2867

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