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Fig. 7 | Cancer Cell International

Fig. 7

From: LncRNA AGAP2 antisense RNA 1 stabilized by insulin-like growth factor 2 mRNA binding protein 3 promotes macrophage M2 polarization in clear cell renal cell carcinoma through regulation of the microRNA-9-5p/THBS2/PI3K-Akt pathway

Fig. 7

Schematic diagram of IGF2BP3/AGAP2-AS1/miR-9-5p/THBS2/PI3K-Akt axis in clear cell renal cell carcinoma. IGF2BP3 stabilizes AGAP2-AS1 through m6A modification and mediates the miR-9-5p/THBS2/PI3K-Akt signaling pathway to affect the M2 polarization of macrophages, thereby participating in renal cell carcinogenesis

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