Fig. 2

CircFNDC3B suppressed OS progression in vitro and in vivo. A Overexpression and knockdown efficiency of circFNDC3B in OS cells evaluated by qRT-PCR. CCK8 assays (B, C), EdU assays (D, E), wound-healing assays (F, G) and transwell assays (H, I) assessing the effects of circFNDC3B overexpression and knockdown on OS cells proliferation, migration and invasion. J, K Xenograft assays assessing the effects of circFNDC3B overexpression or knockdown on OS tumor growth in vivo; scale bar represents 1 cm. Data were shown as the mean ± SD, *P < 0.05, **P < 0.01, ***P < 0.001