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Fig. 3 | Cancer Cell International

Fig. 3

From: Artificial intelligence-driven new drug discovery targeting serine/threonine kinase 33 for cancer treatment

Fig. 3

Z29077885 induces apoptosis. A and B Apoptosis assay for anti-cancer efficacy of Z29077885 in MDA-MB-231 and A549 cell lines was measured by Annexin IV and 7AAD flow cytometry. C cell viability of Z29077885 in MDA-MB-231 and A549 cell lines was taken by bright-field microscopy, bars indicated 200. D Western blot to test STAT3 signaling deactivation by Z29077885 treatment at 12,5 uM in A549 cells. Error bars represent SD over biological replicates. The p values were obtained using One-way ANOVA (*p < 0.05, **p < 0.01, ***p < 0.001)

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