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Fig. 5 | Cancer Cell International

Fig. 5

From: Artificial intelligence-driven new drug discovery targeting serine/threonine kinase 33 for cancer treatment

Fig. 5

The potential of Z29077885 as therapeutics for cancer treatment in vivo. A Anti-cancer efficacy of Z29077885 3D in vitro MDA-MB-231, BT474, MCF-7, and SKBR3 cell lines was taken by bright-field microscopy(right), cell viability was tested by Cell-titer Glo (left). B Z29077885 treatment showed anti-tumor efficacy by reducing tumor size in vivo A549 xenograft. C Enhanced necrosis by Z29077885 treatment in vivo shown by immunohistochemistry. Bars indicated 200 μm. Error bars represent SD over biological replicates. The p values were obtained using One-way ANOVA (*p < 0.05, **p < 0.01, ***p < 0.001)

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Cancer Cell International

ISSN: 1475-2867

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