Fig. 1
From: Role of epithelial splicing regulatory protein 1 in cancer progression
Role of ESRP1 in immune regulation in the tumor microenvironment. ESRP1 plays a pro-tumorigenic role in ovarian cancer by decreasing infiltration of CD8+ T cells in the tumor microenvironment. Conversely, ESRP1 suppresses tumor growth and lung metastasis in bladder cancer in association with polarization of tumor-associated macrophage into antitumor phenotype