Fig. 2
From: Role of epithelial splicing regulatory protein 1 in cancer progression
Regulation of ESRP1 expression. ESRP1 expression is regulated by multiple factors such as transcription factors, epigenetic mechanisms, signaling and tumor microenvironment including oxygen and matrix stiffness at transcriptional and posttranscriptional levels cirRNA, circular RNA; GLI1, GLI family zinc finger 1; GRHL2, grainyhead like transcription factor 2; miRNA, microRNA; NRP2, neuropilin-2; TGF-β, transforming growth factor-β; TRPC6, transient receptor potential channel 6; TWIST1, twist-related protein 1; VEGF, vascular endothelial growth factor; ZEB1/2, zinc finger E-box-binding homeobox 1