Table 1 Prognostic significance of ESRP1 expression in cancer
From: Role of epithelial splicing regulatory protein 1 in cancer progression
No | Cancer type | Association of expression with prognosis | Expression level | Method | References | |
|---|---|---|---|---|---|---|
1 | Colorectal cancer | Favorable prognosis | High → longer overall survival | Gene | qRT-PCR | [48] |
2 | Lung cancer (lung adenocarcinoma) | Favorable prognosis | High → absence of metastases, smaller tumor size, and lower clinical stage | Protein | IHC | [17] |
3 | Lung cancer (non-small-cell lung cancer) | Favorable prognosis | High → longer survival | Protein | IHC | [47] |
4 | Pancreatic cancer | Favorable prognosis | High → longer overall survival | Protein | IHC | [16] |
5 | Pancreatic cancer | Favorable prognosis | High → longer survival | Gene | qRT-PCR | [66] |
6 | Renal cancer (clear cell renal cell carcinoma) | Favorable prognosis | High → longer survival | Gene | Public database analysis (TCGA) | [52] |
7 | Breast cancer | Poor prognosis | High → shorter overall survival | Gene | Public database analysis (GEO dataset) | [19] |
8 | Breast cancer | Favorable prognosis | High → longer survival | Gene | Public database analysis (TCGA) | [52] |
9 | Breast cancer | Poor prognosis | High → shorter distant metastasis-free survival | Gene | Public database analysis (Kaplan − Meier plotter) | [20] |
10 | Breast cancer (ER-positive breast cancer) | Poor prognosis | High → shorter overall survival | Gene | Public database analysis (BreastMark + TCGA) | [21] |
11 | Breast cancer | Poor prognosis | High → shorter relapse-free survival | Gene | Public database analysis (Kaplan − Meier plotter) | [55] |
12 | Ovarian cancer | Poor prognosis | High → progression-free survival | Gene | Public database analysis (TCGA) | [13] |
13 | Prostate cancer | Poor prognosis | High → shorter recurrence-free survival | Gene | Public database analysis (KM-express) | [61] |
14 | Prostate cancer | Poor prognosis | High → shorter biochemical recurrence-free survival, shorter cancer-specific survival | Protein | IHC | [58] |
15 | Prostate cancer | Poor prognosis | High → shorter PSA recurrence-free survival | Protein | IHC | [59] |
16 | Prostate cancer | Poor prognosis | High → biochemical recurrence-free survival | Protein | IHC | [60] |
17 | Skin cancer (melanoma) | Poor prognosis | ESRP-low tumors → trend of more favorable survival | Gene | Public database analysis (TCGA) | [22] |
18 | Skin cancer (cutaneous malignant melanoma) | Poor prognosis | High → shorter overall survival | Gene | Public database analysis | [62] |