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Fig. 3 | Cancer Cell International

Fig. 3

From: RNA m6A methylation regulators in liver cancer

Fig. 3

A positive correlation between HBx and ALKBH5 in HBV-HCC tissues. HBx-ALKBH5 may form a positive feedback loop and participate in HBV-induced hepatocarcinogenesis. HBV upregulates the expression of ALKBH5 through the HBx-WDR5-H3K4me3 axis, and ALKBH5 promotes the stabilization of HBx mRNA by reducing m6A fluctuations, thus forming a positive feedback loop

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Cancer Cell International

ISSN: 1475-2867

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