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Fig. 6 | Cancer Cell International

Fig. 6

From: KCNA1 promotes the growth and invasion of glioblastoma cells through ferroptosis inhibition via upregulating SLC7A11

Fig. 6

Knockdown of SLC7A11 inhibits tumor progression and promotes ferroptosis. A Western blot analysis for siRNA knockdown efficiency of SLC7A11, B CCK-8 assay for cell viability, C Colony formation experiments for cell viability, D Expression of EMT-associated proteins, E Expression of ferroptosis-associated proteins, F–I Measurement of intracellular ROS level (F) intramitochondrial ROS level (G) mitochondrial membrane potential (H) and accumulation of lipid ROS (I). Student’s t-test for two-group comparison. n = 3, *p < 0.05, ***p < 0.001, ****p < 0.0001

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Cancer Cell International

ISSN: 1475-2867

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