Fig. 4

RORα deletion promotes glycolysis induced by 3PO and DHEA in GC cells The changes of ECAR levels in RORα-KO GC cells treated with 3PO (25 µM) or DHEA (250 µM). The glycolysis and glycolytic capacity were measured in the treatment of glucose and oligomycin, respectively. N = 3. All data are represented as the mean ± standard deviation. Vehicle was DMSO. *P < 0.05, **P < 0.01, and ***P < 0.001. Vs. RORα-KO+Vehicle group. ⁺P < 0.05, ⁺⁺P < 0.01, and ⁺⁺⁺P < 0.001. Vs. CON+Vehicle group