Interplay of miRNAs and lncRNAs in STAT3 signaling pathway in colorectal cancer progression

Table 1 MiRNAs directly target the STAT3 signaling pathway

MicroRNA	Up-/down	Oncogene/suppressor	Biological functions	Target gene	Ref.
MiR-29a-5p	Up	Oncogene	Inflammation	STAT3	[57]
MiR-874	Down	Suppressor	Cellular growth, apoptosis	STAT3	[58]
MiR-124	Down	Suppressor	Cellular proliferation, apoptosis	STAT3	[59]
MiR-1299	Down	Suppressor	Proliferation, Apoptosis	STAT3	[60]
MiR-1301	Down	Suppressor	Invasion, Migration	STAT3	[61]
MiR-665	Down	Suppressor	Stemness	STAT3	[62]
MiR-296-5p	Down	Suppressor	Proliferation, migration, invasion	STAT3	[63]

ISSN: 1475-2867