Fig. 2
From: Peroxiredoxin 3 regulates breast cancer progression via ERK-mediated MMP-1 expression
Stable PRDX3 knockdown decreases cell migration and invasion in MDA-MB-231 breast cancer cells. (A) Bar chart of PRDX3 mRNA expression by real-time RT-PCR (left panel) and western blot of PRDX3 protein (right panel) indicating successful knockdown of PRDX3 in MDA-MB-231 cell line. (B) Representative microscopic field of migrated and invaded cells at 100X magnification (left panel). Knockdown of PRDX3 significantly attenuated breast cancer cell migration and invasion. Experiment data are expressed as mean ± SEM; *p < 0.05, **p < 0.01, ***p < 0.001