Fig. 2

Consensus cluster analyses based on CRGs and CRDEGs. (A) Three clusters were divided by consensus cluster analysis coupled with cumulative distribution function plot and delta area plot; (B) Heatmap of CRGs expression allied with clinical characteristic of three clusters; (C) Venn diagram of CRDEGs; (D) Based on CRDEGs, three clusters were divided by consensus cluster analysis coupled with cumulative distribution function and delta area plots; (E) Heatmap of CRDEGs expression combined with other clinical features in three subtype clusters; (F) Variances in CRGs expression level among three gene clusters; (G) Immune infiltration through ssGSEA among the three clusters; (H) OS among three clusters. (I) Principal component analysis (PCA) of the three clusters. (*P < 0.05; ** P < 0.01; and *** P < 0.001; Ns, not significant) OS, overall survival; PCA, principal component analysis; ssGSEA, single sample gene set enrichment analysis. CRGs, cuproptosis-related genes. CRDEGs, cuproptosis-related differentially expressed genes; OS, overall survival