Fig. 3

Analysis of a prognostic score model based on CRDEGs. (A, B) Overall survival (OS) rate and progression free survival (PFS) of the high/low risk groups; (C) Heatmap regarding expression of CRDEGs and survival status of the risk high/low groups; (D, E) Univariate and multivariate cox analysis, green for univariate, and red for multivariate; (F) Nomograph and nomograph prediction diagram for the 1-, 3-, and 5-year OS of NSCLC patients; (G) C-index curve of risk score and other tumor related clinical characteristics; (H) DCA of risk score and other tumor related clinical characteristics; (I) ROC and multiROC curve of risk score and other tumor related clinical characteristics; (J) TMB situation of the prognostic score model risk high/low group; (K, L) Survival probability of TMB high/low group and TMB high/low group plus high/low-risk score. (*P < 0.05; ** P < 0.01; and *** P < 0.001; Ns, not significant). CRDEGs, cuproptosis-related differentially expressed genes; OS, overall survival; PFS, progression free survival; C-index, concordance index; DCA, decision curve analysis; TMB, tumor mutation burden; ROC, receiver operating characteristic curve