Fig. 8

Levels of TFRC and iron content in tumour tissues. A–C The TFRC level in three tumour tissues and its correlation with clinicopathological parameters (scale bar: 100/50 μm). D–F Correlation analysis of the mean optical density values of LASS2 and TFRC. G Prussian blue staining for iron content in the three tumour tissues (scale bar: 50 μm). H Intracellular Fe²⁺ concentration was measured via flow cytometry. I Schematic diagram of the regulatory effect of LASS2 on the metastasis of multiple cancers via ferroptosis. *P < 0.05, ***P < 0.001