Fig. 2
From: C6orf15 promotes liver metastasis via WNT/β-catenin signalling in colorectal cancer
The upregulation of C6orf15 expression promotes the liver metastasis of CRC in mice. a Establishment of a mouse liver metastasis model via the splenic injection of C6orf15-overexpressing MC38 cells and control cells. b Immunohistochemical analysis of C6orf15, Vimentin and ZEB1 expression in the experimental and control groups. c Liver specimens from the two groups were collected and photographed to compare tumour formation (tumour size as well as number), and HE staining was used to visualize pathology. d Western blots show the expression of C6orf15 in tumour samples from both groups