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  1. Hepatocellular carcinoma (HCC) is a major cause of cancer-related death due to early metastasis or recurrence. Tumor angiogenesis plays an essential role in the tumorigenesis of HCC. Accumulated studies have v...

    Authors: Shicheng Xie, Jinwei Zhong, Zhongjing Zhang, Weiguo Huang, Xiaoben Lin, Yating Pan, Xiuyan Kong, Hongping Xia, Zhijie Yu, Haizhen Ni and Jinglin Xia
    Citation: Cancer Cell International 2023 23:159
    Content type: Research Published on:

  2. Chimeric antigen receptor natural killer cells (CAR-NK) promote off-the-shelf cellular therapy for solid tumors and malignancy.However,, the development of CAR-NK is due to their immune surveillance uncertaint...

    Authors: Zahra Hatami, Zahra Sadat Hashemi, Mohamad Eftekhary, Ala Amiri, Vahid Karpisheh, Kaveh Nasrollahi and Reza Jafari
    Citation: Cancer Cell International 2023 23:157
    Content type: Review Published on:

  3. N6-methyladenosine (m6A), 5-methylcytosine (m5C) and N1-methyladenosine (m1A) are the main RNA methylation modifications involved in the progression of cancer. However, it is still unclear whether RNA methylation...

    Authors: Fanxuan Huang, Xinyu Wang, Junzhe Zhong, Hao Chen, Dan Song, Tianye Xu, Kaifu Tian, Penggang Sun, Nan Sun, Jie Qin, Yu Song, Wenbin Ma, Yuxiang Liu, Daohan Yu, Xiangqi Meng, Chuanlu Jiang…
    Citation: Cancer Cell International 2023 23:156
    Content type: Research Published on:

  4. Semaphorins, axon guidance cues in neuronal network formation, have been implicated in cancer progression. We previously identified semaphorin 3 C (SEMA3C) as a secreted protein overexpressed in pancreatic duc...

    Authors: Satoshi Tomizawa, Shigetsugu Takano, Ryotaro Eto, Tsukasa Takayashiki, Satoshi Kuboki and Masayuki Ohtsuka
    Citation: Cancer Cell International 2023 23:155
    Content type: Research Published on:

  5. Gliomas, a type of brain neoplasm, are prevalent and often fatal. Molecular diagnostics have improved understanding, but treatment options are limited. This study investigates the role of INTS9 in processing s...

    Authors: Yu-Chieh Lin, Pei-Chi Chang, Dueng-Yuan Hueng, Shih-Ming Huang and Yao-Feng Li
    Citation: Cancer Cell International 2023 23:154
    Content type: Research Published on:

  6. Despite recent advances in the treatment of lung and breast cancer, the mortality with these two types of cancer is high. Xanthohumol (XN) is known as a bioactive compound that shows an anticancer effect on ca...

    Authors: Zohreh Gholizadeh Siahmazgi, Shiva Irani, Ali Ghiaseddin, Parviz Fallah and Vahid Haghpanah
    Citation: Cancer Cell International 2023 23:153
    Content type: Research Published on:

  7. The accumulation of reactive oxygen species (ROS) in tumor microenvironment (TME) is an important player for tumorigenesis and progression. We aimed to explore the outcomes of ROS on tumor vessels and the pote...

    Authors: Ye Zhao, Jing Yu, Ai Huang, Qin Yang, Guiling Li, Yong Yang and Yeshan Chen
    Citation: Cancer Cell International 2023 23:152
    Content type: Research Published on:

  8. Exosome, a component of liquid biopsy, loaded protein, DNA, RNA and lipid gradually emerges as biomarker in tumors. However, exosomal circRNAs as biomarker and function mechanism in gastric cancer (GC) are not...

    Authors: Xiao-juan Huang, Yan Wang, Hui-ting Wang, Zhao-feng Liang, Cheng Ji, Xiao-xi Li, Lei-lei Zhang, Run-bi Ji, Wen-rong Xu, Jian-hua Jin and Hui Qian
    Citation: Cancer Cell International 2023 23:151
    Content type: Research Published on:

  9. The tumor microenvironment is overwhelmingly dictated by macrophages, intimately affiliated with tumors, exercising pivotal roles in multiple processes, including angiogenesis, extracellular matrix reconfigura...

    Authors: Arian Jahandideh, Mahsa Yarizadeh, Maryam Noei-Khesht Masjedi, Mina Fatehnejad, Romina Jahandideh, Roben Soheili, Yeganeh Eslami, Maryam Zokaei, Ardavan Ahmadvand, Nogol Ghalamkarpour, Rajan Kumar Pandey, Mohsen Nabi Afjadi and Zahra payandeh
    Citation: Cancer Cell International 2023 23:150
    Content type: Research Published on:

  10. Spalt-like protein 4 (SALL4) is a stemness-related transcription factor whose abnormal re-expression contributes to cancer initiation and progression. However, the role of SALL4 in cancer angiogenesis remains ...

    Authors: Fatma A. Abouelnazar, Xiaoxin Zhang, Jiahui Zhang, Maoye Wang, Dan Yu, Xueyan Zang, Jiayin Zhang, Yixin Li, Jing Xu, Qiurong Yang, Yue Zhou, Haozhou Tang, Yanzheng Wang, Jianmei Gu and Xu Zhang
    Citation: Cancer Cell International 2023 23:149
    Content type: Research Published on:

  11. Intrahepatic cholangiocarcinoma (iCCA) presents the similar trend and prevalence of lymph node metastasis to other biliary tract cancer. There is still a necessity and possibility for the current classificatio...

    Authors: Chongyu Zhao, Xiyuan Li, Li Luo, Cheng Chen and Chaobin He
    Citation: Cancer Cell International 2023 23:148
    Content type: Research Published on:

  12. Head and neck squamous cell carcinoma (HNSCC) is a highly aggressive tumor with a 5-year mortality rate of ~ 50%. New in vitro methods are needed for testing patients’ cancer cell response to anti-cancer treat...

    Authors: Aini Hyytiäinen, Katja Korelin, Mervi Toriseva, Tommy Wilkman, Satu Kainulainen, Karri Mesimäki, Johannes Routila, Sami Ventelä, Heikki Irjala, Matthias Nees, Ahmed Al-Samadi and Tuula Salo
    Citation: Cancer Cell International 2023 23:147
    Content type: Research Published on:

  13. Colorectal cancer (CRC) is the third most common cancer in the world. The purpose of this study was to investigate the role of TNNT2 in the proliferation, migration and invasion of CRC cells and its expression...

    Authors: Yifan Liu, Ze Meng, Junqiang Niu, Le Tian, Yishan Chen, Qingju Meng, Yibing Liu and Zhiguo Zhou
    Citation: Cancer Cell International 2023 23:146
    Content type: Research Published on:

    The Correction to this article has been published in Cancer Cell International 2023 23:332

  14. Papillary thyroid carcinoma (PTC) is one of the most common thyroid carcinomas. The gross extrathyroidal extension and extensive metastases of PTC lead to high rates of recurrence and poor clinical outcomes. H...

    Authors: Xiaojun Zhang, Wanwan Peng, Jie Fan, Ruihua Luo, Shanting Liu, Wei Du, Chaochao Luo, Jiawen Zheng, Xinghua Pan and Hong Ge
    Citation: Cancer Cell International 2023 23:145
    Content type: Research Published on:

  15. Myelin and lymphocyte protein 2 (MAL2) is mainly involved in endocytosis under physiological conditions and mediates the transport of materials across the membranes of cell and organelle. It has been reported ...

    Authors: Lijun An, Huiyuan Gong, Xiaojing Yu, Wangming Zhang, Xiaohua Liu, Xiaomin Yang, Liping Shu, Jielin Liu and Liuqi Yang
    Citation: Cancer Cell International 2023 23:144
    Content type: Research Published on:

  16. Matrix stiffness is a mechanical characteristic of the extracellular matrix (ECM) that increases from the tumor core to the tumor periphery in a gradient pattern in a variety of solid tumors and can promote pr...

    Authors: Sadegh Safaei, Roya Sajed, Ahmad Shariftabrizi, Shima Dorafshan, Leili Saeednejad Zanjani, Masoumeh Dehghan Manshadi, Zahra Madjd and Roya Ghods
    Citation: Cancer Cell International 2023 23:143
    Content type: Review Published on:

  17. Numerous mechanisms have shown that long noncoding RNAs (lncRNAs) promote the development of colorectal cancer (CRC), but the role of lnc-LRRTM4 in the progression of CRC remains unclear. In this article, we f...

    Authors: Jingjie Zhang, Xianmei Meng, Yi Zhou, Zhengyu Jiang, Hongsuo Chen, Zhiyi Meng, Qi Zhang and Weichang Chen
    Citation: Cancer Cell International 2023 23:142
    Content type: Research Published on:

  18. ST6GALNAC family members function as sialyltransferases and have been implicated in cancer progression. However, their aberrant expression levels, prognostic values and specific roles in metastatic prostate ca...

    Authors: Meiqian Li, Zhihui Ma, Yuqing Zhang, Hanyi Feng, Yang Li, Weicong Sang, Rujian Zhu, Ruimin Huang and Jun Yan
    Citation: Cancer Cell International 2023 23:141
    Content type: Research Published on:

  20. Authors: Imran Ahmad, Saurabh Pal, Ranjana Singh, Khursheed Ahmad, Nilanjan Dey, Aditi Srivastava, Rumana Ahmad, Muath Suliman, Mohammad Y. Alshahrani, Md. Abul Barkat and Sahabjada Siddiqui
    Citation: Cancer Cell International 2023 23:139
    Content type: Correction Published on:

    The original article was published in Cancer Cell International 2023 23:121

  21. Hepatocellular carcinoma (HCC) is the second malignancy worldwide. POLA2 initiates DNA replication, regulates cell cycle and gene repair that promote tumorigenesis and disease progression. However, the prognos...

    Authors: Long Liu, Qi Wang, Linjun Wu, Lele Zhang, Yuxi Huang, Haihua Yang, Le guo, Zheping Fang and Xuequan Wang
    Citation: Cancer Cell International 2023 23:138
    Content type: Research Published on:

  22. The metastasis of breast cancer (BC) is a complex multi-step pathological process, strictly dependent on the intrinsic characteristics of BC cells and promoted by a predisposing microenvironment. Although immu...

    Authors: Di Xu, Wen-Quan Chen, Ming-Xing Liang, Xiu Chen, Zhen Liu, Yin-Jiao Fei, Xin-Yi Shao, Yang Wu, Wei Zhang and Jin-Hai Tang
    Citation: Cancer Cell International 2023 23:137
    Content type: Research Published on:

  23. Accumulating evidence has confirmed the role of snoRNAs in a variety of cancer, but rare in renal cell carcinoma (RCC). This study aims to clarify the role of snoRNAs in RCC tumorigenesis and their potential a...

    Authors: Yue Zhang, Xiaoling Shang, Miao Yu, Zhao Bi, Kangyu Wang, Qianru Zhang, Li Xie, Xianrang Song and Xingguo Song
    Citation: Cancer Cell International 2023 23:136
    Content type: Research Published on:

  24. A wide range of studies have indicated that microRNAs (miRNAs), a type of small single-stranded regulatory RNAs, are dysregulated in a different variety of human cancers. Therefore, they are expected to play i...

    Authors: Pouriya Sameti, Maryam Tohidast, Mohammad Amini, Seyedeh Zahra Bahojb Mahdavi, Souzan Najafi and Ahad Mokhtarzadeh
    Citation: Cancer Cell International 2023 23:134
    Content type: Review Published on:

  25. Breast cancer (BC) is the most common malignancy in women and the second leading cause of cancer-related death; chemoresistance is still a clinical challenge mainly because of the different molecular features ...

    Authors: Alessia Lo Dico, C. Martelli, F. Corsi, D. Porro, L. Ottobrini and G. Bertoli
    Citation: Cancer Cell International 2023 23:133
    Content type: Research Published on:

  26. Glioma is the most common and aggressive primary malignant brain tumor. Circular RNAs (circRNAs) and RNA-binding proteins (RBPs) have been verified to mediate diverse biological behaviors in various human canc...

    Authors: Jinpeng Hu, Guoqing Zhang, Yongfeng Wang, Kai Xu, Lian Chen, Gang Luo, Jinkun Xu, Hao Li, Dongmei Pei, Xiang Zhao, Zhengting Guo, Xinqiao Li, Shengliang Zong, Yang Jiang and Zhitao Jing
    Citation: Cancer Cell International 2023 23:132
    Content type: Research Published on:

  27. It has been manifested in several studies that age-related metabolic reprogramming is associated with tumor progression, in particular, colorectal cancer (CRC). Here we investigated the role of upregulated met...

    Authors: Chunhua Hu, Mujie Ye, Jianan Bai, Pengfei Liu, Feiyu Lu, Jinhao Chen, Ping Yu, Tiaotiao Chen, Xiaoting Shi and Qiyun Tang
    Citation: Cancer Cell International 2023 23:131
    Content type: Research Published on:

  28. The 5 year survival rate after diagnosis of pancreatic cancer (PANC) is less than 5%, and it is one of the malignant tumors with the worst prognosis. Identification of novel oncogenes involved in the occurrenc...

    Authors: Hui Wu, Anshu Li, Qichang Zheng, Jingyang Gu and Wei Zhou
    Citation: Cancer Cell International 2023 23:130
    Content type: Research Published on:

  29. The gefitinib resistance mechanism in non-small cell lung cancer (NSCLC) remains unclear, albeit exosomal circular RNA (circRNA) is known to possibly play a vital role in it.

    Authors: Si-Liang Wei, Jing-Jing Ye, Li Sun, Lei Hu, Yuan-Yuan Wei, Da-Wei Zhang, Meng-Meng Xu and Guang-He Fei
    Citation: Cancer Cell International 2023 23:129
    Content type: Research Published on:

  30. Myelodysplastic syndrome (MDS) is a clonal bone marrow disorder defined by cytopenia and is associated with an increased risk of transformation to acute myeloid leukemia (AML). The outcome of MDS is poor, so a...

    Authors: Seiichi Okabe, Yuko Tanaka, Mitsuru Moriyama and Akihiko Gotoh
    Citation: Cancer Cell International 2023 23:128
    Content type: Research Published on:

  31. N6-methyladenosine (m6A), one of the most common RNA methylation modifications, has emerged in recent years as a new layer of the regulatory mechanism controlling gene expression in eukaryotes. As a reversible ep...

    Authors: Nan Zhang, Yifei Sun, Zongqin Mei, Zuoshun He and Shiyan Gu
    Citation: Cancer Cell International 2023 23:127
    Content type: Review Published on:

  32. Papillary renal cell carcinoma (pRCC) is a highly metastatic genitourinary cancer and is generally irresponsive to common treatments used for the more prevalent clear-cell (ccRCC) subtype. The goal of this stu...

    Authors: Priyanka F. Karmokar and Nader H. Moniri
    Citation: Cancer Cell International 2023 23:126
    Content type: Research Published on:

  34. Uterine corpus endometrial carcinoma (UCEC) is a gynecological malignant tumor with high incidence and poor prognosis. Although immunotherapy has brought significant survival benefits to advanced UCEC patients...

    Authors: Ganghua Zhang, Zhijing Yin, Jianing Fang, Anshan Wu, Guanjun Chen and Ke Cao
    Citation: Cancer Cell International 2023 23:124
    Content type: Research Published on:

  35. PRKCG encodes PKC γ, which is categorized under the classical protein kinase C family. No studies have specifically established the relationship between PRKCG nsSNPs with structural and functional variations i...

    Authors: Fizzah Abid, Khushbukhat Khan, Yasmin Badshah, Naeem Mahmood Ashraf, Maria Shabbir, Arslan Hamid, Tayyaba Afsar, Ali Almajwal and Suhail Razak
    Citation: Cancer Cell International 2023 23:123
    Content type: Research Published on:

  36. Skin cutaneous melanoma (SKCM) is the most threatening type of skin cancer. Approximately 55,000 people lose their lives every year due to SKCM, illustrating that it seriously threatens human life and health. ...

    Authors: Song He, Yu Ding, Zhonghao Ji, Bao Yuan, Jian Chen and Wenzhi Ren
    Citation: Cancer Cell International 2023 23:122
    Content type: Research Published on:

  37. Breast cancer is the world’s most prevalent cancer among women. Microorganisms have been the richest source of antibiotics as well as anticancer drugs. Moricin peptides have shown antibacterial properties; how...

    Authors: Imran Ahmad, Saurabh Pal, Ranjana Singh, Khursheed Ahmad, Nilanjan Dey, Aditi Srivastava, Rumana Ahmad, Muath Suliman, Mohammad Y. Alshahrani, Md. Abul Barkat and Sahabjada Siddiqui
    Citation: Cancer Cell International 2023 23:121
    Content type: Research Published on:

    The Correction to this article has been published in Cancer Cell International 2023 23:139

  38. Establishing appropriate preclinical models is essential for cancer research. Evidence suggests that cancer is a highly heterogeneous disease. This follows the growing use of cancer models in cancer research t...

    Authors: Mingtang Zeng, Zijing Ruan, Jiaxi Tang, Maozhu Liu, Chengji Hu, Ping Fan and Xinhua Dai
    Citation: Cancer Cell International 2023 23:120
    Content type: Review Published on:

  40. Complexity and heterogeneity of the tumor niche are closely associated with the failure of therapeutic protocols. Unfortunately, most data have been obtained from conventional 2D culture systems which are not ...

    Authors: Maryam Taghavi Narmi, Hanieh Mohajjel Shoja, Sanya Haiaty, Mahdi Mahdipour and Reza Rahbarghazi
    Citation: Cancer Cell International 2023 23:118
    Content type: Research Published on:

  41. As a core member of the FA complex, in the Fanconi anemia pathway, FAAP24 plays an important role in DNA damage repair. However, the association between FAAP24 and patient prognosis in AML and immune infiltration...

    Authors: Xiebing Bao, Jingyun Chi, Yiwei Zhu, Minfeng Yang, Jiahui Du, Zaixiang Tang, Xiaogang Xu, Genxiang Mao, Zhibing Wu, Jun Chen, Jingsheng Hua, Ting Xu and Song-Bai Liu
    Citation: Cancer Cell International 2023 23:117
    Content type: Research Published on:

  42. Cytotoxic anticancer drugs widely used in cancer chemotherapy have some limitations, such as the development of side effects and drug resistance. Furthermore, monotherapy is often less effective against hetero...

    Authors: Kou Nishikubo, Ryuichi Ohgaki, Xingming Liu, Hiroki Okanishi, Minhui Xu, Hitoshi Endou and Yoshikatsu Kanai
    Citation: Cancer Cell International 2023 23:116
    Content type: Research Published on:

  44. Despite the success of cancer therapy, it has encountered a major obstacle due to the complicated nature of cancer, namely resistance. The recurrence and metastasis of cancer occur when anti-cancer therapeutic...

    Authors: Aysooda Hosseinzadeh, Faezeh Poursoleiman, Akram Naghdipour Biregani and Ahmad Esmailzadeh
    Citation: Cancer Cell International 2023 23:114
    Content type: Review Published on:

  45. C-type lectin domain family 1 member B (CLEC1B, encoding the CLEC-2 protein), a member of the C-type lectin superfamily, is a type II transmembrane receptor involved in platelet activation, angiogenesis, and i...

    Authors: Qiangan Jing, Chen Yuan, Chaoting Zhou, Weidong Jin, Aiwei Wang, Yanfang Wu, Wenzhong Shang, Guibing Zhang, Xia Ke, Jing Du, Yanchun Li and Fangchun Shao
    Citation: Cancer Cell International 2023 23:113
    Content type: Research Published on:

  46. Oral squamous cell carcinoma (OSCC) is the predominant histological type of the head and neck squamous cell carcinoma (HNSCC). By comparing the differentially expressed genes (DEGs) in OSCC-TCGA patients with ...

    Authors: Wei-Chen Yen, Kai-Ping Chang, Cheng-Yi Chen, Yenlin Huang, Ting-Wen Chen, Hsing-Wen Cheng, Jui-Shan Yi, Chun-Chia Cheng, Chih-Ching Wu and Chun-I Wang
    Citation: Cancer Cell International 2023 23:112
    Content type: Research Published on:

  47. Glioblastoma is the most common primary central nervous system tumor in adults. Angiotensin II receptor blockers (ARBs) are broadly applied to treat hypertension. Moreover, research has revealed that ARBs have...

    Authors: Yung-Lung Chang, Chung-Hsing Chou, Yao-Feng Li, Li-Chun Huang, Ying Kao, Dueng-Yuan Hueng and Chia-Kuang Tsai
    Citation: Cancer Cell International 2023 23:111
    Content type: Research Published on:

  48. Currently, tumor-treating field (TTField) therapy utilizes a single “optimal” frequency of electric fields to achieve maximal cell death in a targeted population of cells. However, because of differences in ce...

    Authors: Austin R. Smothers, Jason R. Henderson, John J. O’Connell, Jonathan M. Stenbeck, Delphine Dean and Brian W. Booth
    Citation: Cancer Cell International 2023 23:110
    Content type: Research Published on:

  49. Malignant transformation from hepatic fibrosis to carcinogenesis may be a therapeutic target for hepatocellular carcinoma (HCC). The aim of this study was to evaluate anti-cancer efficacy of Pien-Tze-Huang (PZ...

    Authors: Xiangying Yan, Yudong Liu, Congchong Li, Xia Mao, Tengteng Xu, Zhixing Hu, Chu Zhang, Na Lin, Ya Lin and Yanqiong Zhang
    Citation: Cancer Cell International 2023 23:109
    Content type: Research Published on:

  50. Radiotherapy is one of the effective methods for treatment of breast cancer; however, controversies still exist with respect to radiotherapy for patients with TNBC. Here, we intend to explore the mechanism by ...

    Authors: Zhengzheng Zhang, Zhiyan Yao, Zimeng Zhang, Ling Cui, Ling Zhang, Gang Qiu, Xiaotian Song and Shuxia Song
    Citation: Cancer Cell International 2023 23:107
    Content type: Research Published on:
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Cancer Cell International

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